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Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2017 12:39:53 PM
Research Description
Chemical senses, sensory physiology, invertebrate neurobiology.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
The long-term goal of Dr. Alli’s research program is to provide an understanding for the regulation of epithelial sodium channels and MARCKS in essential hypertension and diabetes associated hypertension. There are two areas of focus in the Alli laboratory: 1) to investigate the role of nano-sized vesicles called exosomes in the regulation of sodium transport mechanisms in the aldosterone-sensitive distal nephron, 2) to investigate mechanisms that regulate anionic phospholipid phosphates and MARCKS in the kidney.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/29/2017 12:34:28 PM
Research Description
Molecular mechanisms of age related cognitive decline
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Develop technology and application of magnetic resource imaging and spectroscopy.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/6/2017
Research Description
A variety of neuromuscular diseases result in impaired cough (dystussia) and/or impaired swallow function (dysphagia). Cough and swallows are controlled by complex brainstem networks which, until recently, have been studied in isolation. However, in neuro
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/7/2017 1:58:03 PM
Research Description
Understanding the molecular-physiological-through-behavioral neurobiology of motor, sensory and cognitive plasticity following pharmacotherapy and neurorehabilitation using preclinical (rodent) models of neurotrauma (spinal cord, traumatic brain injuries, stroke) and neurodegenerative diseases.
Department:
Institute for Therapeutic Innovation
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 12:17:44 PM
Research Description
My research focuses on designing optimized therapeutic regimens for antiviral compounds active against viruses that pose a significant threat to global public health including influenza virus, influenza virus, dengue virus, chikungunya virus, hepatitis C virus, and HIV.
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Drug addiction is a chronic disorder that is characterized by compulsive drug taking and relapse after periods of abstinence. The research in our laboratory focuses on the development of non-addictive treatments for nicotine, alcohol, and opioid addiction
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2017 1:53:43 PM
Research Description
Research involves studies on neuroinflammatory mechanisms of blood-brain barrier disruption in ischemic stroke with emphasis on cyclooxygenases and prostanoid signaling.
Department:
Aging & Geriatrics Research
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:05:56 PM
Research Description
Investigates the contribution of age-related increase in adiposity to declining physical and cognitive function and uses a variety of interventions in the reversal of this process including the role of the renin-angiotensin, diet,exercise, the dev of nove
Department:
Oral Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 1:01:02 PM
Research Description
Molecular processes that lead to the establishment of chronic pain; alterations in function of the N-Methyl-D-Aspartate (NMDA) receptor and vanilloid receptor as a result of persistent peripheral stimulation.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2017
Research Description
Investigation of renal, cardiovascular, placental and endometrial function in normal and pathological pregnancies
Department:
Oral Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/6/2017
Research Description
Cellular and Molecular Pain Research Using Whole Cell Patch Clamp Techniques in Rat DRG
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 11:49:31 AM
Research Description
Oral commensal microbiota: Molecular attributes in oral health. Epithelial cell interactions with commensals in protection against pathogens.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/29/2017 11:20:38 AM
Research Description
Metabolism-Diabetes (T2DM); Obesity; Fatty Liver Disease (NAFDL). The main goals of our lab are to understand the metabolic and molecular pathways of T2DM, obesity and NAFLD.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Mitogenic signaling by G protein-coupled receptors; vesicle trafficking.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 9:41:22 AM
Research Description
The neural mechanisms of behavioral and reflex control of breathing. Respiratory sensation mechanisms in various patient populations. Cortical control of breathing. Respiratory rehabilitation in patients with lung disease, stroke, neuromuscular disease an
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 9:07:16 AM
Research Description
Environmental reproductive toxicology in wildlife.
Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 12:56:29 PM
Research Description
Investigation of the clinically relevant anti-oxidant and anti-inflammatory drugs using in vivo preclinical models and human biospecimens of ischemic and hemorrhagic strokes, traumatic brain injury, Alzheimer, and other neurological disorders
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Infectious Diseases, mathematical modeling, chemotherapy, pharmacokinetics, pharmacodynamics, bacteria, virus, and fungi
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Skeletal muscle is the largest organ system in the body and is well known to be important for human health through its contribution to breathing and mobility and through its metabolic role as the primary site of sugar storage and fat metabolism. Our lab studies the role of the molecular clock in regulating skeletal muscle homeostasis and aging.

Tammy Euliano, M.D.

Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
Fetal and maternal Monitoring

Kevin P. Fennelly, MD

Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Assessing infectiousness of tuberculosis and other infections via cough aerosols. ; TB diagnostics
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/19/2017 12:37:53 PM
Research Description
His main research interests are the development of new mass spectrometry technologies for clinical applications such as metabolomics and imaging mass spectrometry applied to biomedical applications. A major goal is to train the next generation of bioanalytical scientists in translational research.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
Forensic toxicology and forensic medicine; addiction medicine
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Our laboratory studies the interplay between epigenetics and chromatin organization in acute myeloid leukemia (AML) and in pre-leukemic conditions. We use biochemistry, cell-based assays, -omics approaches, and genetic in vivo models to understand the molecular mechanisms that drive pre-leukemic clonal evolution and lead to malignant transformation. Our goal is to find and evaluate therapies that will help cancer patients.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2016
Research Description
My area of interest is social determinants of health, impact of stress in childhood on health outcomes, perinatal outcomes.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 2:00:38 PM
Research Description
Neuroimmunopharmacology. Chemokines and chemokine receptors in brain tumors. Focus on glioblastoma and pharmacological targeting using pre-clinical animal models
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/7/2017
Research Description
Loss of arable lands
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 9:13:17 AM
Research Description
My general interests are focused on the mechanisms and control of electrolyte and solute transport across epithelial membranes. In particular, I am interested in transport mechanisms for the oxalate anion across intestinal epithelial in the context of kidney stone disease
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:19:05 PM
Research Description
Cardiovascular neurophysiology and neural mechanisms underlying hypertension.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/9/2015 1:03:49 PM
Research Description
Heart failure and cardiac transplantation, including: investigator-initiated, industry & NIH-sponsored clinical trials.
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 1:22:16 PM
Research Description
1. Study the inflammatory healing response in aneurysms and develop novel tissue-engineered treatments and devices for aneurysms, 2. Study the inflammatory pathways that lead to the development of cerebral aneurysms in a flow-chamber model as well as in vivo animal models
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 12:21:23 PM
Research Description
Regulation of bone remodeling and the generation of new tools for the treatment of bone disease
Department:
Medicinal Chemistry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Biotransformation of drugs and other xenobiotics.
Department:
Surgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 2:19:23 PM
Research Description
Aims to elucidate mechanisms of vascular remodeling that lead to vein graft failure, arterial restenosis, and aortic aneurysm development.

Richard J. Johnson, M.D.

Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Mechanisms of renal injury and progression, including in glomerulonephritis, diabetes, and hypertension.
Department:
Physical Therapy
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 1:31:54 PM
Research Description
Exploration of the molecular mechanisms that cause cancer-associated skeletal muscle wasting and weakness, using cell based models, rodent models and patient biopsies
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
5/24/2016 10:13:40 AM
Research Description
Our current research interest is to understand the function of Nkx2.5, an evolutionarily conserved NK2 class of homeobox transcription factor in mature cardiomyocytes. Within the genomic analysis of cardiovascular diseases, mutations of NKX2.5 (capitals
Department:
Pharmacodynamics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 8:49:20 AM
Research Description
My research interests are the adaptations in endocrine and cardiovascular systems in pregnancy and at birth. The current focus of my research is fetal and neonatal metabolism, including 1)the effect of glucocorticoids on fetal cardiac metabolism and function, and the transition at birth, 2) effects of exposure to Triclosan (an antibacterial in many soaps), and 3) alterations in the maternal microbiome. The laboratory uses a combination of in vivo techniques, including use of telemetry to measure fetal cardiovascular function in utero, biochemical techniques, and systems biology methods- both transcriptomics and metabolomics.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/29/2016 8:05:51 AM
Research Description
Drug design based on naturally occurring toxins affecting brain nicotinic receptors; drug structure-activity relationships
Department:
Biomedical Engineering
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/1/2016
Research Description
The Biomaterial Immuno-Engineering Lab focuses on the engineering of biomaterial-cell interactions, and targeted controlled release of immune modulating factors in order to direct immune cell function.
Department:
Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 9:47:50 AM
Research Description
Mitochondrial autophagy. Mitochondrial dysfunction in ischemia/reperfusion injury to liver, liver aging and hepatotoxicity.
Department:
Microbiology & Cell Science
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 12:21:09 PM
Research Description
Our overall goal is to elucidate the mechanisms by which Leishmania parasites persist in infected hosts. Specifically, we investigate how the parasite's niche within macrophages is formed. In addition, we seek to identify the virulence factors that Leishmania elaborate
Department:
Pharmacodynamics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 3:39:53 PM
Research Description
The Krause laboratory uses genetically modified mice to identify neuronal circuits that promote susceptibility or resiliency to stress-related disease.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 1:13:18 PM
Research Description
Our research focuses on the roles of the CDCP1 protein and the TGF-beta and mTORC1 signaling pathways in breast cancer invasion and metastasis. Our overall goal is to develop innovative and effective drugs for the treatment of human cancers.

Erica Levitt, PharmD, Ph.D.

Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
Prescription opioid overdose is increasing at a rapid rate. Respiratory depression is the primary cause of death from opioid overdose, yet surprisingly little is known about the mechanisms of opioid-induced respiratory depression. Breathing, like other motor behaviors, is coordinated by a network of neurons, primarily situated in the brainstem. I am interested in understanding how opioids modulate these neurons to cause breathing disturbances. A variety of cellular and systems level approaches, including brain slice electrophysiology, single unit and whole nerve recordings from a unique preparation with an intact respiratory network and in vivo-like respiratory cycle, and plethysmography in awake animals are used in pursuit of this goal.
Department:
Neurology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 2:09:37 PM
Research Description
Dr. Li’s research is mainly focused on pathophysiology and experimental therapeutics of dystonia and restless legs syndrome. He is also broadly interested in animal models of movement disorders and in molecular and cellular mechanisms of synaptic plasticity
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Neuroprotection in epileptogenesis
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 3:24:12 PM
Research Description
My group uses sophisticated in vitro and murine infection models to develop regimens for investigational and marketed antibiotics that maximize the killing of bacterial “superbugs” and prevent other bacteria from becoming “superbugs.” The interaction of the immune system with antibiotic(s) to kill microbes is also evaluated.
Department:
Medicinal Chemistry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Dr. Luesch’s multidisciplinary research program at the interface of chemistry and biology combines classical natural products chemistry with high-throughput screening and chemical genomics. It involves most aspects of drug discovery ranging from the collection of promising marine organisms, bioassay development, NMR spectroscopic structure determination, total synthesis, mechanism-of-action studies, and pharmacology, up to the preclinical and clinical development of candidate molecules. His lab is producing a small but increasing pipeline of bioactive compounds that are at various developmental stages. He also uses functional genomics approaches to identify and characterize genes associated with disease processes, especially cancer and neurological disorders.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/27/2016
Research Description
Research Interests: The identification of novel targets for the treatment of cardiac arrhythmias. In particular, we are interested in therapies for atrial fibrillation, which is the most common cardiac arrhythmia affecting more than 2 million Americans. We are interested in the regulation of voltage-gated potassium (Kv) channels that are vital for atrial repolarization in the human heart. Work in our laboratory is devoted to understanding the details of Kv channel regulation, trafficking, and pharmacological modulation and how this is all integrated into the broader context of normal cardiomyocyte signaling and the pathogenesis of disease. A second major focus of our laboratory is signaling in olfactory sensory neurons and the molecular mechanism that regulate our sense of smell. Olfactory loss affect millions of Americans and can result from age, head trauma, infection, drugs, or other causes. Recently, we have demonstrated olfactory dysfunction as a clinical manifestation of an emerging class of human genetic disorders, termed ciliopathies, which involve defects in ciliary assembly and/or protein transport. Importantly, we are developing gene therapeutic approaches to successfully rescue anosmia resulting from the malformation/loss of cilia and other forms of olfactory loss. Projects in the laboratory are dedicated to understanding the mechanisms regulating sensory neuron function, the mechanism and penetrance of diseases and disorders that cause anosmia, and development of therapeutic strategies to treat patients with a loss of smell.
Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 4:20:16 PM
Research Description
Mechanisms of long-term central and systemic abnormalities induced by neonatal exposure to general anesthesia. Mechanisms underlying the causes of epilepsy in phenylketonuria (PKU).
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2015 10:53:49 AM
Research Description
Molecular mechanisms of hematopoietic growth factor-induced cell signaling events regulating cell growth & apoptosis of normal and malignant hematopoietic cells; interleukin-3 regulation of tyrosine and serine/threonine protein kinases;
Department:
Psychiatry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 3:43:34 PM
Research Description
Behavioral effects of drug of abuse used recreationally (e.g. cocaine) and medicinally (e.g. opioid painkillers) in rats.
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/6/2017 11:50:20 AM
Research Description
Genomic Bases of Memory and Neuronal Evolution. Our laboratory works to characterize basic mechanisms underlying the design of nervous systems and evolution of neuronal signaling mechanisms. The major questions are: (1) why are individual neurons so different? (2) How do learning and memory store in neuronal genomes and neural circuits? (3) How to restore memories? (4) How to make a neuron and a brain?
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
We use molecular biological, anatomical and behavioral approaches to understand how receptors and signal transduction cascades contribute to chemosensory detection in olfactory, taste, and endocrine systems.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/3/2016 9:53:20 AM
Research Description
Neurophysiology of pain; inflammation and neuropathic pain; chronic pain mechanisms; translational research for chronic pain.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/23/2016 9:06:07 AM
Research Description
Genetic models for human vascular diseases; Studying pathogenetic mechanism of vascular malformation and pulmonary arterial hypertension: Preclinical studies targeting vascular malformatuon; development of the vascular system; Role of macrophages in development of arteriovenous malformations.
Department:
Neurology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 2:50:57 PM
Research Description
Dr. Okun’s laboratory has focused on identifying the physiological brain signature patterns for tics and other movement disorders, and also has been focused on the development of neurotechnology for a closed loop solution to tic disorders. Dr. Okun’s research efforts have also been focused on the motor and non-motor aspects of deep brain stimulation as applied to basal ganglia disorders.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2017
Research Description
Physiology, pharmacology, and biophysics of neurotransmitter receptors especially the function of nicotinic acetylcholine receptors in the brain. We are additionally interested in addiction and the development of drug cessation therapies for smokers and people addicted to the use of betel quid.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2015 9:48:27 AM
Research Description
Nitric oxide biology. Molecular mechanisms of oxidant-induced lung cell injury; lung toxicology.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Signal transduction mechanism of angiotensin regulation of norepinephrine neuromodulation in the brain; antisense targating of renin/angiotensin to control cardiovascular diseases; gene therapy, neurobiology, brain cytokines in neurogenic hypertension.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:38:42 PM
Research Description
Hepatotoxicity, immunotoxicity, metabolism, kinetics and risk assessment, nanotoxicology
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 10:48:51 AM
Research Description
neurodegenerative diseases and gene therapy research.
Department:
Anesthesiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Understanding the mechanisms behind nicotine toxicity at cellular level as it relates to alterations in gene expression.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2017
Research Description
Topoisomerases; cancer and microbial chemotherapy; mitochondrial DNA; chromatin structure. Malaria, plastid/organellar DNA and anti-malarial drugs.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 9:49:27 AM
Research Description
Obesity and metabolic syndrome: inflammatory and prodiabetic effects of hyperuricemia and underlying signaling mechanisms responsible for these effects; role of ketohexokinase in the pathogenesis of obesity and the metabolic syndrome; molecular signaling; Intercellular communications in the adipose tissue (adipocytes, endothelial cells): signal transduction, exosomes, transcriptomics
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 2:06:21 PM
Research Description
Cellular and biochemical mechanisms by which G protein-coupled receptors activate physiologically important tyrosine kinase signaling pathways.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/1/2016 12:31:28 PM
Research Description
Effects of stress and chronic elevations in glucocorticoids on central nervous system control of cardiovascular function.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
The focus of our lab is to investigate mechanisms of endothelial dysfunction and increased risk of atherosclerotic disease in unique patient populations. Our investigations range from bench research to translational studies involving patients with acute kidney injury, chronic kidney disease, or lupus.
Department:
Radiation Oncology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2016 2:11:20 PM
Research Description
Our research laboratory seeks to improve cancer therapies through molecular targeting strategies and physiologic interventions such as exercise. A primary focus is the tumor microenvironment which not only influences treatment resistance of cancer to conventional anticancer therapies but also plays a critical role in neoplastic cell initiation, malignant progression, and metastatic spread to secondary sites.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Membrane transport of amino acids and organic solutes in cultured brain cells and epithelial cells.

Lee Sweeney, Ph.D.

Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
neuromuscular diseases
Department:
Chemistry
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 2:04:06 PM
Research Description
Molecular Medicine; Nanomedicine; Chemical Biology; Bioanalytical chemistry; Biomedical Engineering
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
12/18/2015
Research Description
Dr. Torres’ research focuses on the regulation of dopamine homeostasis, the physiological role of brain specific orphan transporters and the biological function of the dystonia-related torsinA protein.
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:44:11 PM
Research Description
Oxidative stress, Aging and central regulation of blood pressure.

Nikhil Urs, Ph.D.

Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017
Research Description
Dr. Urs’ laboratory is to study the role of genetic and environmental factors on dopamine neurotransmission and learn more about the dopamine system by deciphering a) receptor signaling pathways involved in DA neurotransmission, b) functional dopamine neuronal circuits and c) how these integrate and manifest behaviorally in an organism.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 12:01:59 PM
Research Description
Drug use in food producing animals; pharmacokinetic modelling
Department:
Radiation Oncology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 7:52:38 AM
Research Description
Electrolyte and nutrient transport alteration in acute infectious and non infectious diarrheal conditions using electrophysiological techniques.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/29/2016
Research Description
Development of technology for the noninvasive monitoring of gene & stem cell transfer in skeletal and cardiac muscle; bioengineering of skeletal muscle, studies the effect of gene gene transfer and correction from the level of the cell to the humans. Basic muscle physiology and pathophysiology related to the muscular dystrophies.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 1:16:01 PM
Research Description
Cellular & molecular mechanisms of renal ammonia transport & acid-base homeostasis; mechanisms and regulation of ammonia transport in intestinal epithelial, roles of altered glutamate neurotransmission in neurological conditions; animal models & molecular approaches to study the roles of mammalian ammonia transporters.

Daniel Wesson, Ph.D.

Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
Dr. Wesson’s research focuses on the neural processing of sensory information in the context of behavior and specific hypotheses regarding the neural basis of sensory dysfunction in neurological disorders, including dementias and addiction, wherein sensory processing is aberrant. Dr. Wesson’s lab investigates a variety of methods to monitor neural activity ranging from multi-site electrophysiological recordings and imaging, to cutting-edge operant behavioral assays to allow for understanding the contributions of specific cell-types to behaviors.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 3:19:06 PM
Research Description
Development and motor control of masticatory muscles. injury and repair of masticatory muscles; orofacial pain models.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 8:06:41 AM
Research Description
Aldosterone action & hyperaldosteronism, renal endothelin action, hypertension, ion transporting ATPases; K+ channels; signal transduction.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
Fetal neuroendocrine development and cardiovascular physiology.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 2:02:24 PM
Research Description
electrophysiological property of non-excitable cells; intercellular & intracellular calcium signaling pathways; functional role of purinergic signaling; functional role of P2X & P2Y receptors in SGK1-regulated ion transport in the kidney.
Department:
Medicine-Jax
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Role of H+ V-ATPase and novel secondary transporter Na+ or K+/H+ antiporter
Department:
Pharmacology & Therapeutics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
We are interested in understanding the fundamental biology of the interactions between genetic factors and environmental factors in the process of animal aging.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/12/2017
Research Description
Crohn’s Disease, Inflammatory Bowel Disease (IBD), Ulcerative Colitis 1) Molecular mechanism of fibrosis in Crohn's disease. The goal of this project is to determine the molecular mechanism whereby inflammation contributes to fibrosis in Crohn's disease using animal and cell culture models of the disease. 2) Therapy directed at preventing or treating fibrosis in IBD. The goal of this project is to identify pathways or novel therapies to prevent or treat fibrosis in Crohn’s disease. 3) Noninvasive method to detect fibrosis in Crohn's disease patients. The goal of this translational project is to develop methods to noninvasively detect fibrosis. This method will be used to monitor the natural history of Crohn's disease and determine the ability of new medications to alter the natural history of the disease. 4) Intestinal drug targeting. The goal of this work is to more effectively deliver drugs to regions of bowel using the oral route. This is aimed at decreasing systemic side effects of immunosuppressive medications. 5) Delivery of clinical care to IBD patients. Several prospective and retrospective projects examine pathogenesis, disease assessment, disease complications, and therapy outcomes in Crohn's disease and ulcerative colitis. A special area of interest is in care of college students with Crohn’s disease and ulcerative colitis.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
AAV vector design. AAV vector production.
Department:
Physiological Sciences
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 9:09:54 AM
Research Description
Neural control of cardiovascular physiology, neurogenic hypertension, bone marrow hematopoiesis and immune responses in cardiovascular diseases. Host-microbiota interaction in hypertension.

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