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Results
- Department:
- Whitney Laboratories
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/15/2017 12:39:53 PM
- Research Description
- Chemical senses, sensory physiology, invertebrate neurobiology.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017
- Research Description
- The long-term goal of Dr. Alli’s research program is to provide an understanding for the regulation of epithelial sodium channels and MARCKS in essential hypertension and diabetes associated hypertension. There are two areas of focus in the Alli laboratory: 1) to investigate the role of nano-sized vesicles called exosomes in the regulation of sodium transport mechanisms in the aldosterone-sensitive distal nephron, 2) to investigate mechanisms that regulate anionic phospholipid phosphates and MARCKS in the kidney.
- Department:
- Neuroscience
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/29/2017 12:34:28 PM
- Research Description
- Molecular mechanisms of age related cognitive decline
- Department:
- Neuroscience
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Develop technology and application of magnetic resource imaging and spectroscopy.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/6/2017
- Research Description
- A variety of neuromuscular diseases result in impaired cough (dystussia) and/or impaired swallow function (dysphagia). Cough and swallows are controlled by complex brainstem networks which, until recently, have been studied in isolation. However, in neuro
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/7/2017 1:58:03 PM
- Research Description
- Understanding the molecular-physiological-through-behavioral neurobiology of motor, sensory and cognitive plasticity following pharmacotherapy and neurorehabilitation using preclinical (rodent) models of neurotrauma (spinal cord, traumatic brain injuries, stroke) and neurodegenerative diseases.
- Department:
- Institute for Therapeutic Innovation
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 12:17:44 PM
- Research Description
- My research focuses on designing optimized therapeutic regimens for antiviral compounds active against viruses that pose a significant threat to global public health including influenza virus, influenza virus, dengue virus, chikungunya virus, hepatitis C virus, and HIV.
- Department:
- Psychiatry
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Drug addiction is a chronic disorder that is characterized by compulsive drug taking and relapse after periods of abstinence. The research in our laboratory focuses on the development of non-addictive treatments for nicotine, alcohol, and opioid addiction
- Department:
- Neuroscience
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/15/2017 1:53:43 PM
- Research Description
- Research involves studies on neuroinflammatory mechanisms of blood-brain barrier disruption in ischemic stroke with emphasis on cyclooxygenases and prostanoid signaling.
- Department:
- Aging & Geriatrics Research
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 12:05:56 PM
- Research Description
- Investigates the contribution of age-related increase in adiposity to declining physical and cognitive function and uses a variety of interventions in the reversal of this process including the role of the renin-angiotensin, diet,exercise, the dev of nove
- Department:
- Oral Surgery
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 1:01:02 PM
- Research Description
- Molecular processes that lead to the establishment of chronic pain; alterations in function of the N-Methyl-D-Aspartate (NMDA) receptor and vanilloid receptor as a result of persistent peripheral stimulation.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/15/2017
- Research Description
- Investigation of renal, cardiovascular, placental and endometrial function in normal and pathological pregnancies
- Department:
- Oral Surgery
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/6/2017
- Research Description
- Cellular and Molecular Pain Research Using Whole Cell Patch Clamp Techniques in Rat DRG
- Department:
- Oral Biology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017 11:49:31 AM
- Research Description
- Oral commensal microbiota: Molecular attributes in oral health. Epithelial cell interactions with commensals in protection against pathogens.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/29/2017 11:20:38 AM
- Research Description
- Metabolism-Diabetes (T2DM); Obesity; Fatty Liver Disease (NAFDL). The main goals of our lab are to understand the metabolic and molecular pathways of T2DM, obesity and NAFLD.
- Department:
- Anatomy & Cell Biology
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017
- Research Description
- Mitogenic signaling by G protein-coupled receptors; vesicle trafficking.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 9:41:22 AM
- Research Description
- The neural mechanisms of behavioral and reflex control of breathing. Respiratory sensation mechanisms in various patient populations. Cortical control of breathing. Respiratory rehabilitation in patients with lung disease, stroke, neuromuscular disease an
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/26/2017
- Research Description
- Dr. de Kloet’s research program is broadly focused on elucidating mechanisms underlying obesity and co-morbid conditions such as hypertension and diabetes. A particular emphasis is placed on the interactions among the neural circuits that regulate energy balance with those that control blood pressure, and also on the impact that the renin-angiotensin system has on these circuits. Some specific research topics currently being explored include: the impact of high-fat diet on angiotensin-sensitive neural circuits; the role of angiotensin-II and related peptides in the neuroendocrine regulation of energy balance; optogenetic targetting of angiotensin-sensitive neurons of the nodose ganglion to combat obesity and hypertension; mechanisms by which angiotensin-senstive neurons of the median preoptic nucleus coordinate physiological and pathophysiological responses to hypertensive stimuli; mechanisms linking angiotensin-sensitive neurons and thermogenic responses to pertubations in energy balance and blood pressure regulation.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017 9:07:16 AM
- Research Description
- Environmental reproductive toxicology in wildlife.
- Department:
- Anesthesiology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017 12:56:29 PM
- Research Description
- Investigation of the clinically relevant anti-oxidant and anti-inflammatory drugs using in vivo preclinical models and human biospecimens of ischemic and hemorrhagic strokes, traumatic brain injury, Alzheimer, and other neurological disorders
- Department:
- Medicine
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Infectious Diseases, mathematical modeling, chemotherapy, pharmacokinetics, pharmacodynamics, bacteria, virus, and fungi
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Skeletal muscle is the largest organ system in the body and is well known to be important for human health through its contribution to breathing and mobility and through its metabolic role as the primary site of sugar storage and fat metabolism. Our lab studies the role of the molecular clock in regulating skeletal muscle homeostasis and aging.
Tammy Euliano, M.D.
- Department:
- Anesthesiology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017
- Research Description
- Fetal and maternal Monitoring
Kevin P. Fennelly, MD
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Assessing infectiousness of tuberculosis and other infections via cough aerosols. ; TB diagnostics
- Department:
- Pathology, Immunology & Laboratory Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/19/2017 12:37:53 PM
- Research Description
- His main research interests are the development of new mass spectrometry technologies for clinical applications such as metabolomics and imaging mass spectrometry applied to biomedical applications. A major goal is to train the next generation of bioanalytical scientists in translational research.
- Department:
- Pathology, Immunology & Laboratory Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017
- Research Description
- Forensic toxicology and forensic medicine; addiction medicine
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Our laboratory studies the interplay between epigenetics and chromatin organization in acute myeloid leukemia (AML) and in pre-leukemic conditions. We use biochemistry, cell-based assays, -omics approaches, and genetic in vivo models to understand the molecular mechanisms that drive pre-leukemic clonal evolution and lead to malignant transformation. Our goal is to find and evaluate therapies that will help cancer patients.
- Department:
- Pathology, Immunology & Laboratory Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2016
- Research Description
- My area of interest is social determinants of health, impact of stress in childhood on health outcomes, perinatal outcomes.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 2:00:38 PM
- Research Description
- Neuroimmunopharmacology. Chemokines and chemokine receptors in brain tumors. Focus on glioblastoma and pharmacological targeting using pre-clinical animal models
- Department:
- Whitney Laboratories
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/7/2017
- Research Description
- Loss of arable lands
- Department:
- Pathology, Immunology & Laboratory Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 9:13:17 AM
- Research Description
- My general interests are focused on the mechanisms and control of electrolyte and solute transport across epithelial membranes. In particular, I am interested in transport mechanisms for the oxalate anion across intestinal epithelial in the context of kidney stone disease
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 12:19:05 PM
- Research Description
- Cardiovascular neurophysiology and neural mechanisms underlying hypertension.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/9/2015 1:03:49 PM
- Research Description
- Heart failure and cardiac transplantation, including: investigator-initiated, industry & NIH-sponsored clinical trials.
- Department:
- Neurosurgery
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 1:22:16 PM
- Research Description
- 1. Study the inflammatory healing response in aneurysms and develop novel tissue-engineered treatments and devices for aneurysms, 2. Study the inflammatory pathways that lead to the development of cerebral aneurysms in a flow-chamber model as well as in vivo animal models
- Department:
- Orthodontics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017 12:21:23 PM
- Research Description
- Regulation of bone remodeling and the generation of new tools for the treatment of bone disease
- Department:
- Medicinal Chemistry
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Biotransformation of drugs and other xenobiotics.
- Department:
- Surgery
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/6/2017 2:19:23 PM
- Research Description
- Aims to elucidate mechanisms of vascular remodeling that lead to vein graft failure, arterial restenosis, and aortic aneurysm development.
Richard J. Johnson, M.D.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Mechanisms of renal injury and progression, including in glomerulonephritis, diabetes, and hypertension.
- Department:
- Physical Therapy
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 1:31:54 PM
- Research Description
- Exploration of the molecular mechanisms that cause cancer-associated skeletal muscle wasting and weakness, using cell based models, rodent models and patient biopsies
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/24/2017 10:13:40 AM
- Research Description
- Our current research interest is to understand the function of Nkx2.5, an evolutionarily conserved NK2 class of homeobox transcription factor in mature cardiomyocytes. Within the genomic analysis of cardiovascular diseases, mutations of NKX2.5 (capitals
- Department:
- Pharmacodynamics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017 8:49:20 AM
- Research Description
- My research interests are the adaptations in endocrine and cardiovascular systems in pregnancy and at birth. The current focus of my research is fetal and neonatal metabolism, including 1)the effect of glucocorticoids on fetal cardiac metabolism and function, and the transition at birth, 2) effects of exposure to Triclosan (an antibacterial in many soaps), and 3) alterations in the maternal microbiome. The laboratory uses a combination of in vivo techniques, including use of telemetry to measure fetal cardiovascular function in utero, biochemical techniques, and systems biology methods- both transcriptomics and metabolomics.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/25/2017 8:05:51 AM
- Research Description
- Drug design based on naturally occurring toxins affecting brain nicotinic receptors; drug structure-activity relationships
- Department:
- Biomedical Engineering
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/1/2016
- Research Description
- The Biomaterial Immuno-Engineering Lab focuses on the engineering of biomaterial-cell interactions, and targeted controlled release of immune modulating factors in order to direct immune cell function.
- Department:
- Surgery
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017 9:47:50 AM
- Research Description
- Mitochondrial autophagy. Mitochondrial dysfunction in ischemia/reperfusion injury to liver, liver aging and hepatotoxicity.
- Department:
- Microbiology & Cell Science
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/6/2017 12:21:09 PM
- Research Description
- Our overall goal is to elucidate the mechanisms by which Leishmania parasites persist in infected hosts. Specifically, we investigate how the parasite's niche within macrophages is formed. In addition, we seek to identify the virulence factors that Leishmania elaborate
- Department:
- Pharmacodynamics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 3:39:53 PM
- Research Description
- The Krause laboratory uses genetically modified mice to identify neuronal circuits that promote susceptibility or resiliency to stress-related disease.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 1:13:18 PM
- Research Description
- Our research focuses on the roles of the CDCP1 protein and the TGF-beta and mTORC1 signaling pathways in breast cancer invasion and metastasis. Our overall goal is to develop innovative and effective drugs for the treatment of human cancers.
Erica Levitt, PharmD, Ph.D.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017
- Research Description
- Prescription opioid overdose is increasing at a rapid rate. Respiratory depression is the primary cause of death from opioid overdose, yet surprisingly little is known about the mechanisms of opioid-induced respiratory depression. Breathing, like other motor behaviors, is coordinated by a network of neurons, primarily situated in the brainstem. I am interested in understanding how opioids modulate these neurons to cause breathing disturbances. A variety of cellular and systems level approaches, including brain slice electrophysiology, single unit and whole nerve recordings from a unique preparation with an intact respiratory network and in vivo-like respiratory cycle, and plethysmography in awake animals are used in pursuit of this goal.
- Department:
- Neurology
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 2:09:37 PM
- Research Description
- Dr. Li’s research is mainly focused on pathophysiology and experimental therapeutics of dystonia and restless legs syndrome. He is also broadly interested in animal models of movement disorders and in molecular and cellular mechanisms of synaptic plasticity
- Department:
- Neurology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Neuroprotection in epileptogenesis
- Department:
- Medicine
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/6/2017 3:24:12 PM
- Research Description
- My group uses sophisticated in vitro and murine infection models to develop regimens for investigational and marketed antibiotics that maximize the killing of bacterial “superbugs” and prevent other bacteria from becoming “superbugs.” The interaction of the immune system with antibiotic(s) to kill microbes is also evaluated.
- Department:
- Medicinal Chemistry
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Dr. Luesch’s multidisciplinary research program at the interface of chemistry and biology combines classical natural products chemistry with high-throughput screening and chemical genomics. It involves most aspects of drug discovery ranging from the collection of promising marine organisms, bioassay development, NMR spectroscopic structure determination, total synthesis, mechanism-of-action studies, and pharmacology, up to the preclinical and clinical development of candidate molecules. His lab is producing a small but increasing pipeline of bioactive compounds that are at various developmental stages. He also uses functional genomics approaches to identify and characterize genes associated with disease processes, especially cancer and neurological disorders.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/27/2016
- Research Description
- Research Interests: The identification of novel targets for the treatment of cardiac arrhythmias. In particular, we are interested in therapies for atrial fibrillation, which is the most common cardiac arrhythmia affecting more than 2 million Americans. We are interested in the regulation of voltage-gated potassium (Kv) channels that are vital for atrial repolarization in the human heart. Work in our laboratory is devoted to understanding the details of Kv channel regulation, trafficking, and pharmacological modulation and how this is all integrated into the broader context of normal cardiomyocyte signaling and the pathogenesis of disease. A second major focus of our laboratory is signaling in olfactory sensory neurons and the molecular mechanism that regulate our sense of smell. Olfactory loss affect millions of Americans and can result from age, head trauma, infection, drugs, or other causes. Recently, we have demonstrated olfactory dysfunction as a clinical manifestation of an emerging class of human genetic disorders, termed ciliopathies, which involve defects in ciliary assembly and/or protein transport. Importantly, we are developing gene therapeutic approaches to successfully rescue anosmia resulting from the malformation/loss of cilia and other forms of olfactory loss. Projects in the laboratory are dedicated to understanding the mechanisms regulating sensory neuron function, the mechanism and penetrance of diseases and disorders that cause anosmia, and development of therapeutic strategies to treat patients with a loss of smell.
- Department:
- Anesthesiology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017 4:20:16 PM
- Research Description
- Mechanisms of long-term central and systemic abnormalities induced by neonatal exposure to general anesthesia. Mechanisms underlying the causes of epilepsy in phenylketonuria (PKU).
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/24/2017 10:53:49 AM
- Research Description
- Molecular mechanisms of hematopoietic growth factor-induced cell signaling events regulating cell growth & apoptosis of normal and malignant hematopoietic cells; interleukin-3 regulation of tyrosine and serine/threonine protein kinases;
- Department:
- Psychiatry
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 3:43:34 PM
- Research Description
- Behavioral effects of drug of abuse used recreationally (e.g. cocaine) and medicinally (e.g. opioid painkillers) in rats.
- Department:
- Whitney Laboratories
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/6/2017 11:50:20 AM
- Research Description
- Genomic Bases of Memory and Neuronal Evolution. Our laboratory works to characterize basic mechanisms underlying the design of nervous systems and evolution of neuronal signaling mechanisms. The major questions are: (1) why are individual neurons so different? (2) How do learning and memory store in neuronal genomes and neural circuits? (3) How to restore memories? (4) How to make a neuron and a brain?
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017
- Research Description
- We use molecular biological, anatomical and behavioral approaches to understand how receptors and signal transduction cascades contribute to chemosensory detection in olfactory, taste, and endocrine systems.
- Department:
- Orthodontics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/24/2017 9:53:20 AM
- Research Description
- Neurophysiology of pain; inflammation and neuropathic pain; chronic pain mechanisms; translational research for chronic pain.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 5/23/2016 9:06:07 AM
- Research Description
- Genetic models for human vascular diseases; Studying pathogenetic mechanism of vascular malformation and pulmonary arterial hypertension: Preclinical studies targeting vascular malformatuon; development of the vascular system; Role of macrophages in development of arteriovenous malformations.
- Department:
- Neurology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 2:50:57 PM
- Research Description
- Dr. Okun’s laboratory has focused on identifying the physiological brain signature patterns for tics and other movement disorders, and also has been focused on the development of neurotechnology for a closed loop solution to tic disorders. Dr. Okun’s research efforts have also been focused on the motor and non-motor aspects of deep brain stimulation as applied to basal ganglia disorders.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/15/2017
- Research Description
- Physiology, pharmacology, and biophysics of neurotransmitter receptors especially the function of nicotinic acetylcholine receptors in the brain. We are additionally interested in addiction and the development of drug cessation therapies for smokers and people addicted to the use of betel quid.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/10/2015 9:48:27 AM
- Research Description
- Nitric oxide biology. Molecular mechanisms of oxidant-induced lung cell injury; lung toxicology.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Signal transduction mechanism of angiotensin regulation of norepinephrine neuromodulation in the brain; antisense targating of renin/angiotensin to control cardiovascular diseases; gene therapy, neurobiology, brain cytokines in neurogenic hypertension.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 12:38:42 PM
- Research Description
- Hepatotoxicity, immunotoxicity, metabolism, kinetics and risk assessment, nanotoxicology
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 10:48:51 AM
- Research Description
- neurodegenerative diseases and gene therapy research.
- Department:
- Anesthesiology
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Understanding the mechanisms behind nicotine toxicity at cellular level as it relates to alterations in gene expression.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/15/2017
- Research Description
- Topoisomerases; cancer and microbial chemotherapy; mitochondrial DNA; chromatin structure. Malaria, plastid/organellar DNA and anti-malarial drugs.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/12/2017 9:49:27 AM
- Research Description
- Obesity and metabolic syndrome: inflammatory and prodiabetic effects of hyperuricemia and underlying signaling mechanisms responsible for these effects; role of ketohexokinase in the pathogenesis of obesity and the metabolic syndrome; molecular signaling; Intercellular communications in the adipose tissue (adipocytes, endothelial cells): signal transduction, exosomes, transcriptomics
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017 2:06:21 PM
- Research Description
- Cellular and biochemical mechanisms by which G protein-coupled receptors activate physiologically important tyrosine kinase signaling pathways.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/1/2016 12:31:28 PM
- Research Description
- Effects of stress and chronic elevations in glucocorticoids on central nervous system control of cardiovascular function.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017
- Research Description
- The focus of our lab is to investigate mechanisms of endothelial dysfunction and increased risk of atherosclerotic disease in unique patient populations. Our investigations range from bench research to translational studies involving patients with acute kidney injury, chronic kidney disease, or lupus.
- Department:
- Radiation Oncology
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2016 2:11:20 PM
- Research Description
- Our research laboratory seeks to improve cancer therapies through molecular targeting strategies and physiologic interventions such as exercise. A primary focus is the tumor microenvironment which not only influences treatment resistance of cancer to conventional anticancer therapies but also plays a critical role in neoplastic cell initiation, malignant progression, and metastatic spread to secondary sites.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 7/24/2017
- Research Description
- 1) Gut microbiome; 2) membrane transporters, peptidases, and receptors for amino acids and bioactive peptides; 3) Innate immunity and inflammation
Lee Sweeney, Ph.D.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- neuromuscular diseases
- Department:
- Chemistry
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 2:04:06 PM
- Research Description
- Molecular Medicine; Nanomedicine; Chemical Biology; Bioanalytical chemistry; Biomedical Engineering
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 12/18/2015
- Research Description
- Dr. Torres’ research focuses on the regulation of dopamine homeostasis, the physiological role of brain specific orphan transporters and the biological function of the dystonia-related torsinA protein.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 12:44:11 PM
- Research Description
- Oxidative stress, Aging and central regulation of blood pressure.
Nikhil Urs, Ph.D.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017
- Research Description
- Dr. Urs’ laboratory is to study the role of genetic and environmental factors on dopamine neurotransmission and learn more about the dopamine system by deciphering a) receptor signaling pathways involved in DA neurotransmission, b) functional dopamine neuronal circuits and c) how these integrate and manifest behaviorally in an organism.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 12:01:59 PM
- Research Description
- Drug use in food producing animals; pharmacokinetic modelling
- Department:
- Radiation Oncology
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/26/2017 7:52:38 AM
- Research Description
- Electrolyte and nutrient transport alteration in acute infectious and non infectious diarrheal conditions using electrophysiological techniques.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/24/2017
- Research Description
- Measurement of skeletal and cardiac muscle physiology, function, and metabolism using innovative NMR and MRI based techniques. Studies the effect of gene transfer/pharmacological correction from the basic cell level to humans with muscular dystrophies.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/26/2017 1:16:01 PM
- Research Description
- Cellular & molecular mechanisms of renal ammonia transport & acid-base homeostasis; mechanisms and regulation of ammonia transport in intestinal epithelial, roles of altered glutamate neurotransmission in neurological conditions; animal models & molecular approaches to study the roles of mammalian ammonia transporters.
Daniel Wesson, Ph.D.
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017
- Research Description
- Dr. Wesson’s research focuses on the neural processing of sensory information in the context of behavior and specific hypotheses regarding the neural basis of sensory dysfunction in neurological disorders, including dementias and addiction, wherein sensory processing is aberrant. Dr. Wesson’s lab investigates a variety of methods to monitor neural activity ranging from multi-site electrophysiological recordings and imaging, to cutting-edge operant behavioral assays to allow for understanding the contributions of specific cell-types to behaviors.
- Department:
- Orthodontics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/12/2017 3:19:06 PM
- Research Description
- Development and motor control of masticatory muscles. injury and repair of masticatory muscles; orofacial pain models.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017 8:06:41 AM
- Research Description
- Aldosterone action & hyperaldosteronism, renal endothelin action, hypertension, ion transporting ATPases; K+ channels; signal transduction.
- Department:
- Physiology & Functional Genomics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017
- Research Description
- Fetal neuroendocrine development and cardiovascular physiology.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017 2:02:24 PM
- Research Description
- electrophysiological property of non-excitable cells; intercellular & intracellular calcium signaling pathways; functional role of purinergic signaling; functional role of P2X & P2Y receptors in SGK1-regulated ion transport in the kidney.
- Department:
- Medicine-Jax
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/22/2015
- Research Description
- Role of H+ V-ATPase and novel secondary transporter Na+ or K+/H+ antiporter
- Department:
- Pharmacology & Therapeutics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/13/2017
- Research Description
- We are interested in understanding the fundamental biology of the interactions between genetic factors and environmental factors in the process of animal aging.
- Department:
- Medicine
- Concentrations:
- Accepting Students
- Yes
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 7/12/2017
- Research Description
- Crohn’s Disease, Inflammatory Bowel Disease (IBD), Ulcerative Colitis 1) Molecular mechanism of fibrosis in Crohn's disease. The goal of this project is to determine the molecular mechanism whereby inflammation contributes to fibrosis in Crohn's disease using animal and cell culture models of the disease. 2) Therapy directed at preventing or treating fibrosis in IBD. The goal of this project is to identify pathways or novel therapies to prevent or treat fibrosis in Crohn’s disease. 3) Noninvasive method to detect fibrosis in Crohn's disease patients. The goal of this translational project is to develop methods to noninvasively detect fibrosis. This method will be used to monitor the natural history of Crohn's disease and determine the ability of new medications to alter the natural history of the disease. 4) Intestinal drug targeting. The goal of this work is to more effectively deliver drugs to regions of bowel using the oral route. This is aimed at decreasing systemic side effects of immunosuppressive medications. 5) Delivery of clinical care to IBD patients. Several prospective and retrospective projects examine pathogenesis, disease assessment, disease complications, and therapy outcomes in Crohn's disease and ulcerative colitis. A special area of interest is in care of college students with Crohn’s disease and ulcerative colitis.
- Department:
- Pediatrics
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - No
- Last Updated
- 6/13/2017
- Research Description
- AAV vector design. AAV vector production.
- Department:
- Physiological Sciences
- Concentrations:
- Accepting Students
- No
- Accepting Students if
Funding Obtained - Yes
- Last Updated
- 6/12/2017 9:09:54 AM
- Research Description
- Neural control of cardiovascular physiology, neurogenic hypertension, bone marrow hematopoiesis and immune responses in cardiovascular diseases. Host-microbiota interaction in hypertension.