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Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 11:04:28 AM
Research Description
Our laboratory is interested in the molecular and cellular basis of aging. There are a number of mechanisms that contribute to the aging process at the molecular and cellular level. These mechanisms include, but are not limited to: (1) molecular damage
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2016
Research Description
The goal of our work is to understand how misfolded alpha-1-antitrypsin causes cellular injury in liver and innate immune cells and to develop rational therapies to modulate this injury. To accomplish this goal we use cellular and animal models and transl
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 12:16:39 PM
Research Description
Regulation of immunity & autoimmunity; prediction, intervention, and treatment for type 1 diabetes. The lab is focused on the mechanisms by which regulatory T cells maintain peripheral immune tolerance in the context of type 1 diabetes.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 9:11:54 AM
Research Description
Cell biology and biochemistry of actin-binding proteins involved in apoptosis, angiogenesis, neural plasticity and cancer biology.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
5/31/2016
Research Description
Characterize the immune suppressor mehanisms involved in the develeopment of HCC in the background of cirrhosis to identify novel targets that can lead to development of new immune activating strategies and/or prognostic and predictive immune biomarkers.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 12:07:02 PM
Research Description
My laboratory is examining mechanisms for loss of human beta cells in type 1 diabetes and ways to regenerate functional beta cell mass. Studies are conducted using human biospecimens, isolated islets, and beta cell lines with experiments focused on the role of neurotransmitters and neurohormones in beta cell regeneration. Techniques include IHC, ISH, laser microdissection, microscopy (brightfield, fluorescence, confocal), in vitro cell proliferation/apoptosis, transfection, RNA and RNAseq analysis, Western blot, and other molecular biology techniques.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017
Research Description
host-pathogen interactions; adaptive immune responses of chronic and tropical diseases.
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 1:09:57 PM
Research Description
The current research projects are 1) studies of microRNAs in the regulation of toll-like receptor signaling pathways in innate immune response and their relationship to autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus and periodontal disease; 2) oral cancer pathogenesis and development of immunotherapy for these cancers.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2016 7:47:33 AM
Research Description
Translational research Cell-based therapy for type 1 diabetes Dr. Clare-Salzler is a JDRF, NIH-funded basic and clinical scientist investigating the autoimmune process that causes Type 1 Diabetes (T1D). The major focus of the laboratory is on the role o
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 2:58:49 PM
Research Description
The Cogle Research Group is focused on clinical and laboratory research in stem cells and cancer. Projects include: (a) identification of novel agents & pathways for treatment of blood cancers, (b) using genomics to understand origins of blood cancers, (c) using genomics to understand drug response, discover new biomarkers and identify new drugs for treatment of patients with blood cancers.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017
Research Description
Developmental Biology & Evolution: Embryonic development of genitourinary organs; Genetic & genomic mechanisms of animal evolution; Genetic and environmental causes of birth defects
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Mitogenic signaling by G protein-coupled receptors; vesicle trafficking.
Department:
Vet Med- Research
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Systems Biology of Vector Borne Disease Transmission Dynamics: Multi-OMICS approaches to dissecting fundamental host-pathogen interactions. Discovery of novel interventions in the fight against malaria requires a pioneering approach to examine cell-cell interactions among the transmission stages of the parasite (i.e., sporozoite and ookinete) and their respective mammalian or mosquito host cells.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Mechanisms and regulation of lysosomal degradation of cellular proteins and organelles in normal and diseased states. Therapeutic regulation of autophagy, pathway of organelle degradation, to treat cancer and other diseases.
Department:
Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/15/2017
Research Description
Dr. Efron has a professional interest in surgical critical care and trauma, both clinically as well as in the laboratory. He conducts basic science and translational research in sepsis and inflammation. He is currently one of the principal investigators for an NIH-funded P50 center grant for the UF Sepsis and Critical Illness Research Center to study the persistent inflammation, immunosuppression and catabolism syndrome (PICS) following sepsis in surgical intensive care unit patients. He also has his own NIH R01 funding regarding examining the hematopoietic response of the elderly to severe trauma. He was mentored by and now collaborates with Drs. Moldawer, Baker and Leeuwenburgh.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
7/6/2017 9:03:36 AM
Research Description
Over the last five years, my lab has explored the function of carbonic anhydrase IX (CAIX) expression and activity in breast cancer. We hypothesize that CAIX is involved in regulating extracellular pH to the advantage of tumor cells.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/19/2017
Research Description
Prevention and Reversal of Type 1 diabetes
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 9:13:17 AM
Research Description
My general interests are focused on the mechanisms and control of electrolyte and solute transport across epithelial membranes. In particular, I am interested in transport mechanisms for the oxalate anion across intestinal epithelial in the context of kidney stone disease
Department:
Ophthalmology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 12:20:14 PM
Research Description
Gene expression, and gene delivery, gene therapy and functional genomics in the retina.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 1:44:54 PM
Research Description
Gene and stem cell therapies
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 12:21:23 PM
Research Description
Regulation of bone remodeling and the generation of new tools for the treatment of bone disease
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
Research in the Huang lab is concentrated on elucidating molecular mechanisms associated with breast and ovarian cancer metastasis.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Chromatin structure and gene regulation; Epigenetic regulation of stem cell function and hematopoiesis; Structure and function of chromatin insulator.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 9:52:19 AM
Research Description
Chemoresistance in breast and prostate cancer, Nuclear Structure and Function, Epigenetic Regulation of Gene Expression tumor Suppression
Department:
Surgery
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 2:19:23 PM
Research Description
Aims to elucidate mechanisms of vascular remodeling that lead to vein graft failure, arterial restenosis, and aortic aneurysm development.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017
Research Description
Dr. Jobin is interested in bacteria/host interactions and ensuring innate/immunological responses during health and diseases. The intestine poses an interesting conundrum – it must peacefully cohabit with a sea of commensal bacteria (~100 trillion) and a high load of bacterial products, but swiftly respond to the presence of pathogenic micro-organisms that threaten its integrity. A major clinical consequence of deregulated bacteria/host interaction in the intestine is the development of inflammatory bowel diseases (IBD) and colorectal cancer. Using mice and zebrafish housed in germ-free and gnotobiotic conditions, microbiome techniques (next-generation sequencing, microbial gene mutations, microbial RNA-sequence, etc.), Dr. Jobin studies the differential contribution of bacteria in protecting or exacerbating development of colitis and colorectal cancer. Dr. Jobin has contributed to the understanding of the cellular and molecular mechanism regulating host response to bacterial colonization, and has published numerous papers on innate signaling events taking place in the intestine and how these impact intestinal homeostasis.

Richard J. Johnson, M.D.

Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Mechanisms of renal injury and progression, including in glomerulonephritis, diabetes, and hypertension.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
5/24/2016 10:13:40 AM
Research Description
Our current research interest is to understand the function of Nkx2.5, an evolutionarily conserved NK2 class of homeobox transcription factor in mature cardiomyocytes. Within the genomic analysis of cardiovascular diseases, mutations of NKX2.5 (capitals
Department:
Surgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 9:47:50 AM
Research Description
Mitochondrial autophagy. Mitochondrial dysfunction in ischemia/reperfusion injury to liver, liver aging and hepatotoxicity.
Department:
Urology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/15/2017 10:44:30 AM
Research Description
Our research is focused on tumor immunology, including immunotherapy and mechanisms of immune escape in urologic cancers (prostate, kidney, bladder) in both clinical and experimental settings.
Department:
Aging & Geriatrics Research
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 2:26:46 PM
Research Description
Physiology, biology & biochemistry of aging, with focus on MITOCHONDRIAL BIOLOGY, AUTOPHAGY, apoptosis and oxidative stress. Aging, oxidative stress, MITOCHONDRIA, AUTOPHAGY apoptosis, ant-aging interventIONS.
Department:
Chemical Engineering
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
Dr. Lele’s research is in the area of mechanobiology. We are interested in the mechanisms by which mechanical stresses on the nucleus impact gene expression in health and disease. The lab combines cutting edge microscope techniques, biophysical assays, genomics and molecular biology approaches to address hypotheses. Current collaborations are with Jonathan Licht (Director of Cancer Center), Jeffrey Nickerson (Anatomy and Cell Biology, U Mass medical school), Kyle Roux (Sanford Research), Richard Dickinson (UF Che) and Gregg Gundersen (Cell Biology, Columbia University). The lab has NIH-funded openings for PhD students.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 1:15:25 PM
Research Description
Cancer epigenetics focusing on enzymes (KATs and HDACs) that regulate protein acetylation using molecular, cellular and chemical biology approaches. We are also interested in discovering and optimizing small-molecule inhibitors of these enzymes for cancer therapy. Cancer metabolism is another area of research interest.
Department:
Whitney Laboratories
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 1:42:19 PM
Research Description
Regulation of cell differentiation in the vertebrate retina and CNS and the molecular physiology of disease vector mosquito larvae. Molecular physiology of larval mosquito gut epithelium. Ageing of the cochlea.
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 1:10:27 PM
Research Description
Epigenetic and metabolic regulation of tumor progression.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2015 10:53:49 AM
Research Description
Molecular mechanisms of hematopoietic growth factor-induced cell signaling events regulating cell growth & apoptosis of normal and malignant hematopoietic cells; interleukin-3 regulation of tyrosine and serine/threonine protein kinases;

Peter McFetridge, Ph.D.

Department:
Biomedical Engineering
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 11:46:34 AM
Research Description
Vascular remodeling, wound healing and tissue engineering (vascular/bone/cartilage)
Department:
Periodontology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/3/2016
Research Description
We focus primarily on osteoimmunology, which is the study of interactions between immune cells, immune mediators, and immune signaling in skeletal biology. In particular, we study the differentiation of bone-resorbing osteoclast cells in response to bone
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/31/2016 12:49:46 PM
Research Description
Role of tumor suppressor APC in initiation & progression of colorectal cancer; transcriptional regulation of APC gene & its role in breast carcinogenesis; mechanisms of secondhand smoking-induced lung and breast carcinogenesis; Targeting ATR/Chk1 pathway for therapeutic development of colorectal cancer.
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 3:02:22 PM
Research Description
Studies on the cellular and molecular bases for inherited peripheral neuropathies and approaches to attenuate the accumulation of misfolded proteins within cells. Schwann cell biology, myelin formation, small molecule therapies and dietary approaches
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/23/2016 9:06:07 AM
Research Description
Genetic models for human vascular diseases; Studying pathogenetic mechanism of vascular malformation and pulmonary arterial hypertension: Preclinical studies targeting vascular malformatuon; development of the vascular system; Role of macrophages in development of arteriovenous malformations.
Department:
Pediatrics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 1:47:12 PM
Research Description
Various stem cell (i.e. bone marrow, fetal, iPSCsand hepatic) biology and how they can be used as a tool in gene therapy or in their participation in liver regeneration. Also looking into how hepatic cells (hepatocytes, ductular cells, stellate cells) can be used in developing a bio-artificial liver device (BAL), bioengineering
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Molecular mechanisms of pathogenesis of gram-negative anaerobic bacterial species; bacterial/host cell interactions
Department:
Biochemistry & Molecular Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/22/2015
Research Description
Neuronal cytoskeletal proteins especially microtubules, microfilaments and their associated proteins. Enzyme catalysis and regulation.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
7/6/2017 1:46:35 PM
Research Description
Structure and function of Histone deacetylases, and their roles in gene regulation and cancer.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017
Research Description
Genetic imprinting mechanisms and mouse models of imprinting disorders. Epigenetic reprogramming during germ cell development.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/1/2016
Research Description
Defining the cellular and molecular mechanisms by which T cells contribute to immunity against respiratory pathogens
Department:
Neuroscience
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:34:09 PM
Research Description
Cellular and molecular mechanisms underlying normal and pathogenetic development of the cerebral cortex.
Department:
Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
Yes
Last Updated
6/12/2017 9:49:27 AM
Research Description
Obesity and metabolic syndrome: inflammatory and prodiabetic effects of hyperuricemia and underlying signaling mechanisms responsible for these effects; role of ketohexokinase in the pathogenesis of obesity and the metabolic syndrome; molecular signaling; Intercellular communications in the adipose tissue (adipocytes, endothelial cells): signal transduction, exosomes, transcriptomics
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
5/23/2016 9:19:26 AM
Research Description
My laboratory works on the fundamental biology of stem cells. Our goal is to design test and bring new cell based therapies to the clinic. How stem cells are involved in cancer and the creation of a supportive "cancer niche" are two primary areas of res
Department:
Whitney Laboratories
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/10/2016 12:57:21 PM
Research Description
Research focus:the cellular and molecular mechanisms of development and regeneration in annelids and other closely related marine animals. Interests: patterning of embryonic stem cells, neurogenesis, regenerative biology and patterning of the germline.
Department:
Medicine
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017
Research Description
The focus of our lab is to investigate mechanisms of endothelial dysfunction and increased risk of atherosclerotic disease in unique patient populations. Our investigations range from bench research to translational studies involving patients with acute kidney injury, chronic kidney disease, or lupus.
Department:
Entomology & Nematology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/25/2016
Research Description
Genetic transformation of the obligate intracellular bacterium, Wolbachia, and it's use in paratransgenic introgression of genetic elements in insects.
Department:
Aging & Geriatrics Research
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 1:08:06 PM
Research Description
Molecular mechanisms underlying cochlear aging, detoxification, and age-related hearing loss
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 12:49:45 PM
Research Description
Application of patient induced pluripotent stem (iPS) cells to clinical translational research;The role of mitochondrial ATP transporters in embryonic development, organ homeostasis and reproduction
Department:
Neurosurgery
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
4/11/2016
Research Description
My research program is focused understanding the mechanism of cancer metastasis and dormancy. The epithelial mesenchymal transition (EMT) is now suggested to play an important role in the initial invasion during cancer metastasis. However, direct in vivo evidence is currently lacking. Our lab is interested in understanding how cancer EMT contributes to cancer metastasis, and if so whether it also regulates cancer dormancy, a phenomenon in which micrometastatic disease is present in multiple organs but clinically undetectable.
Department:
Ophthalmology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 12:00:46 PM
Research Description
Dr. Tuli is board-certified in ophthalmology. Her interests include cataracts, corneal transplants, ocular surface cancers, dry eye disease and infectious eye diseases.
Department:
Radiation Oncology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/26/2017 7:52:38 AM
Research Description
Electrolyte and nutrient transport alteration in acute infectious and non infectious diarrheal conditions using electrophysiological techniques.
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/13/2017 4:37:29 PM
Research Description
The Vitriol lab uses live cell and super resolution microscopy to study the actin cytoskeleton in cell motility, neural development, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/26/2017 11:42:06 AM
Research Description
Molecular and epigenetic mechanisms infection and other inflammatory conditions underlying inflammatory polarization of antigen presenting cells (APC) including macrophages and dentritic cells in infectious disease (HIV-1) and autoimmune disease (type 1 diabetes).
Department:
Oral Biology
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017 3:22:14 PM
Research Description
The major focus of my research program is dedicated to the understanding of homeostatic mechanisms which are disrupted in autoimmunity, inflammatory diseases and cancer processes. I have investigated regulatory mechanisms ranging from those associated with the adaptive immune response [regulatory T cells and dendritic cells] and innate immune responses [monocytes, macrophages and neutrophils] to those associated with mucosal homeostasis [epithelial cell immune responses]. In short, I spent my formal training deciphering the lack of regulatory responses in type 1 diabetes (T1D) using the non-obese diabetic (NOD) mouse model; developing therapies to improve this phenomenon; and finally evaluating mechanisms of therapeutic efficacy (or lack thereof). In recent years, I have focused my research on the role of epithelial and stromal cells in innate immune responses and how these non-traditional innate mediators contribute to immune tolerance, systemic immunity, and cancer progression.
Department:
Physiology & Functional Genomics
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
No
Last Updated
6/29/2016
Research Description
Development of technology for the noninvasive monitoring of gene & stem cell transfer in skeletal and cardiac muscle; bioengineering of skeletal muscle, studies the effect of gene gene transfer and correction from the level of the cell to the humans. Basic muscle physiology and pathophysiology related to the muscular dystrophies.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/1/2016
Research Description
We study microsatellite repeat expansion diseases, including myotonic dystrophy. We use molecular, cellular, computational, and animal-based approaches to understand basic mechanisms that cause symptoms in this and related multi-systemic diseases, as well as identify treatments that will help patients. We also study RNA localization at a basic level, to understand why and how RNA molecules move to different places in the cell. We seek to combine high-throughput genomics approaches with single molecule imaging approaches to characterize and understand this new frontier in biology.
Department:
Orthodontics
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/12/2017 3:19:06 PM
Research Description
Development and motor control of masticatory muscles. injury and repair of masticatory muscles; orofacial pain models.
Department:
Molecular Genetics & Microbiology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/21/2017 8:49:14 AM
Research Description
We are studying cancer cell signaling with expertise in signal transduction, genetic and epigenetic regulation, and animal models. Our current laboratory research is centered on two families of transcriptional co-activators, MAML and CRTC, which are essential components of Notch receptor signaling and LKB1-CRTC/CREB signaling pathways, respectively. We are investigating the molecular regulation and the roles of deregulated cell signaling in cancer generation and progression, with the goal of gaining molecular insights into cancer pathogenesis and identifying novel cancer diagnostic and therapeutic targets.
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
6/13/2017
Research Description
Mechanisms of irisin on converting white adipose tissue into brown adipose tissue for fighting obesity and type 2 diabetes; Roles of mesenchymal stem cells in regulating hematopoietic "niches" in normal and lupus patients; Transdifferentiation of human
Department:
Pathology, Immunology & Laboratory Medicine
Concentrations:
Accepting Students
No
Accepting Students if
Funding Obtained
No
Last Updated
5/23/2016 2:15:42 PM
Research Description
1. Molecular defects in immunoglobulin transcriptome repertoires in health and disease. 2. HIV-1 population structure, evolution, persistence and activation during disease progression. 3. HPV prevalence, population structure, persistence and fluctuation
Department:
Anatomy & Cell Biology
Concentrations:
Accepting Students
Yes
Accepting Students if
Funding Obtained
Yes
Last Updated
6/19/2017 11:49:55 AM
Research Description
Mechanism of oncogenic transformation. Cooperation of oncogenes and suppressor genes in cancer development. Genetically engineered mice models for cancer. Targeted therapeutics in pancreatic and lung cancer models.

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